Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- ELISA [1]
- Immunohistochemistry [4]
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Validation data
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- Product number
- HYB 131-01-02 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Anti-MBL2 Monoclonal Antibody (3B6)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- HYB 131-01B-005 is specific for MBL from human serum or plasma. HYB 131-01B-005 has been successfully used in ELISA. Used as detection antibody in sandwich ELISA with a mannan or HYB 131-01B-005 coat, HYB 131-01B-005 is selective for normally oligomerized MBL. The HYB 131-01B-005 immunogen is MBL purified from human donor plasma. Epitope specificity differs from that of HYB 131-10-02 and HYB 131-11-02. Epitope is near the carbohydrate-binding site. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/ml
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 3B6
- Vial size
- 200 µl
- Concentration
- 1.04 mg/ml
- Storage
- 4° C, store in dark
Submitted references Interaction of lectin pathway of complement-activating pattern recognition molecules with mycobacteria.
A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus.
Characterization of the interaction between serum mannan-binding protein and nucleic acid ligands.
L-ficolin binding and lectin pathway activation by acetylated low-density lipoprotein.
Binding of serum mannan binding lectin to a cell integrity-defective Cryptococcus neoformans ccr4Delta mutant.
Effect of stages of lactation on the concentration of a 90-kilodalton heat shock protein in bovine mammary tissue.
Bartlomiejczyk MA, Swierzko AS, Brzostek A, Dziadek J, Cedzynski M
Clinical and experimental immunology 2014 Nov;178(2):310-9
Clinical and experimental immunology 2014 Nov;178(2):310-9
A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus.
Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV
The Journal of biological chemistry 2010 Aug 6;285(32):24729-39
The Journal of biological chemistry 2010 Aug 6;285(32):24729-39
Characterization of the interaction between serum mannan-binding protein and nucleic acid ligands.
Nakamura N, Nonaka M, Ma BY, Matsumoto S, Kawasaki N, Asano S, Kawasaki T
Journal of leukocyte biology 2009 Sep;86(3):737-48
Journal of leukocyte biology 2009 Sep;86(3):737-48
L-ficolin binding and lectin pathway activation by acetylated low-density lipoprotein.
Faro J, Chen Y, Jhaveri P, Oza P, Spear GT, Lint TF, Gewurz H
Clinical and experimental immunology 2008 Feb;151(2):275-83
Clinical and experimental immunology 2008 Feb;151(2):275-83
Binding of serum mannan binding lectin to a cell integrity-defective Cryptococcus neoformans ccr4Delta mutant.
Panepinto JC, Komperda KW, Hacham M, Shin S, Liu X, Williamson PR
Infection and immunity 2007 Oct;75(10):4769-79
Infection and immunity 2007 Oct;75(10):4769-79
Effect of stages of lactation on the concentration of a 90-kilodalton heat shock protein in bovine mammary tissue.
Watanabe A, Miyamoto T, Katoh N, Takahashi Y
Journal of dairy science 1997 Oct;80(10):2372-9
Journal of dairy science 1997 Oct;80(10):2372-9
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Sandwich ELISA of Mannan-Binding Lectin using HYB 131-01 as the capture antibody and HYB 131-01B as the biotinylated detection antibody.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of HYB 131-01-02 in human liver cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Mannan-Binding Lectin in liver carcinoma using a Mannan-Binding Lectin monoclonal antibody (Product # HYB 131-01-02).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Mannan-Binding Lectin in paraffin-embedded human liver tissue using a Mannan-Binding Lectin monoclonal antibody (Product # HYB 131-01-02).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of Mannan-Binding Lectin in paraffin-embedded human liver tissue using a Mannan-Binding Lectin monoclonal antibody (Product # HYB 131-01-02).